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Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD
Published on: October 10, 2012
[Morphometric study of the grouped lymphoid nodules in Wistar rats with different behavioral activity exposed to
Abstract:
This paper describes the results of the study of the structural elements of the grouped lymphoid nodules (GLN, Peyer's patches) of rat ileum after the exposure to emotional-painful stress. In the control group of behaviorally passive rats, the area, occupied by GLN structural elements in the intestinal sections, was significantly greater than that one in the group of active rats. After the exposure to stress, the areas of all GLN structural components were decreased in the behaviorally passive rats. In the group of behaviorally active rats exposed to stress, the areas occupied by the GLN internodular zones, were increased, while the areas of lymphoid nodules remained practically unchanged, suggesting high adaptation capacity of this group of animals.

