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Related Concept Videos

Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...

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Related Experiment Video

Updated: Jun 19, 2026

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
04:09

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors

Published on: February 13, 2026

Mucosal prolapse syndrome presenting as rectal polyposis.

L A A Brosens1, E A Montgomery, B S Bhagavan

  • 1Department of Pathology, University Medical Center, Utrecht, The Netherlands. L.A.A.Brosens@umcutrecht.nl

Journal of Clinical Pathology
|October 29, 2009
PubMed
Summary

Mucosal prolapse syndrome, often misdiagnosed, can present as rectal polyposis. Recognizing this rare variant of solitary rectal ulcer syndrome improves diagnosis and prevents incorrect treatment.

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Last Updated: Jun 19, 2026

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Published on: February 13, 2026

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Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Pathology

Background:

  • Mucosal prolapse syndrome (MPS) encompasses diverse conditions unified by mucosal prolapse.
  • Variable presentations lead to frequent misdiagnosis and delayed treatment.

Observation:

  • A patient presented with symptoms mimicking colorectal polyposis syndrome, exhibiting multiple rectal polyps.
  • Histopathological review and medical history revealed a rare variant of solitary rectal ulcer syndrome (SRUS).

Findings:

  • Rectal polyposis can be an atypical manifestation of SRUS/MPS.
  • This presentation highlights the diagnostic challenges associated with MPS.

Implications:

  • Improved recognition of rectal polyposis in SRUS/MPS enhances diagnostic accuracy.
  • Timely and appropriate management can be initiated, avoiding inappropriate interventions.