Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intraoperative colonic lavage: failure to decrease mucosal microflora.

M B Smith1, P Baliga, W M Sartor

  • 1Department of Surgery, Tulane University School of Medicine, New Orleans, La 70112.

Southern Medical Journal
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hand-arm vibration exposure and outcomes after cubital tunnel surgery.

Occupational medicine (Oxford, England)·2026
Same author

Evidence for the Collective Nature of Radial Flow in Pb+Pb Collisions with the ATLAS Detector.

Physical review letters·2026
Same author

Evidence for the Dimuon Decay of the Higgs Boson in pp Collisions with the ATLAS Detector.

Physical review letters·2025
Same author

Evidence for Longitudinally Polarized W Bosons in the Electroweak Production of Same-Sign W Boson Pairs in Association with Two Jets in pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

Physical review letters·2025
Same author

Conceptualising a theoretical framework for planning and evaluating workplace oral health promotion programs.

Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals·2023
Same author

Workplace oral health promotion activities among community-aged care workers: A qualitative exploration.

Community dentistry and oral epidemiology·2023
Same journal

SMA's 6th Annual Physicians-in-Training Leadership Conference Abstract Presentations.

Southern medical journal·2026
Same journal

Potential Impact of Lower Federal Loan Availability on Medical Education in Appalachia.

Southern medical journal·2026
Same journal

Experiential Mentorship Skills Training: The Effect on Real-Life Mentoring.

Southern medical journal·2026
Same journal

Social Pressure: How Early Social Context Shapes Career Interest in Medicine.

Southern medical journal·2026
Same journal

Comparing Speed and Accuracy of Artificial Intelligence Large Language Models on the Orthopedic In-Training Examination.

Southern medical journal·2026
Same journal

Don't Wait to Talk about Weight: A 2-Hour Interactive Curriculum Improves Medical Student Skills with Weight Management.

Southern medical journal·2026
See all related articles

Intraoperative colonic lavage significantly reduced intraluminal bacteria but failed to impact mucosal-associated bacteria. This may explain high infection rates after emergency colorectal surgery.

Area of Science:

  • Gastroenterology
  • Microbiology
  • Surgical Research

Background:

  • Limited data exist on intraoperative colonic lavage's effect on colonic bacterial counts.
  • The impact on mucosa-associated bacteria remains unknown, despite their potential role in surgical site infections.

Purpose of the Study:

  • To investigate the effect of intraoperative colonic lavage on both intraluminal and mucosal colonic microflora.
  • To assess the efficacy of mechanical lavage in reducing bacterial colonization in different colonic niches.

Main Methods:

  • 10 adult male Sprague-Dawley rats underwent intraoperative colonic washout.
  • Quantitative and qualitative aerobic and anaerobic cultures were performed on intraluminal and mucosal samples.
  • Scanning electron microscopy examined the colon wall's bacterial colonization.

Related Experiment Videos

Main Results:

  • Mechanical lavage achieved 1000-fold to 10,000-fold reductions in aerobic and anaerobic intraluminal flora.
  • No significant reduction was observed in aerobic or anaerobic mucosal bacteria.
  • Scanning electron microscopy provided visual evidence of bacterial presence on the mucosa.

Conclusions:

  • Intraoperative colonic lavage is effective at reducing intraluminal bacteria but not mucosa-associated bacteria.
  • The failure to diminish mucosal bacterial colonization may contribute to persistent high infection rates following emergency colorectal surgery.