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Updated: Jun 19, 2026

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Aseptic Laboratory Techniques: Volume Transfers with Serological Pipettes and Micropipettors
Published on: May 31, 2012
A MECHANICAL MEASURING INSTRUMENT FOR STERILE LIQUIDS
1Laboratories of The Rockefeller Institute for Medical Research.
The Journal of Experimental Medicine
|October 30, 2009
Summary
A new instrument mechanically measures and delivers precise liquid volumes, replacing graduated pipettes in immunological tests. This sterile liquid measurement device ensures accuracy and prevents contamination in sensitive experiments.
Area of Science:
- Biomedical Engineering
- Laboratory Instrumentation
- Immunology
Background:
- Graduated pipettes are commonly used for liquid measurements in immunological experiments.
- Current methods may pose risks of contamination and require manual precision.
- Standardized and sterile liquid handling is crucial for reproducible experimental outcomes.
Purpose of the Study:
- To introduce a novel instrument for the mechanical measurement and delivery of aliquot liquid portions.
- To provide an alternative to graduated pipettes for setting up immunological serum tests.
- To ensure sterile liquid measurements without contamination risk.
Main Methods:
- The study describes a newly developed mechanical instrument for liquid handling.
- The instrument is designed for precise measurement of variable liquid volumes.
- It facilitates sterile delivery of liquids, crucial for immunological assays.
Main Results:
- The instrument accurately measures and delivers aliquot portions of liquids.
- It successfully replaces the need for graduated pipettes in serum test setups.
- Sterile liquid measurement is achieved, preventing sample contamination.
Conclusions:
- The described instrument offers a reliable and sterile method for liquid measurement in immunological experiments.
- Its design allows for adjustable volumes, enhancing experimental flexibility.
- The device has potential applications in various procedures requiring precise, sterile handling of small liquid volumes.
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