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Updated: Jun 19, 2026

Implementation of a Permeable Membrane Insert-based Infection System to Study the Effects of Secreted Bacterial Toxins on Mammalian Host Cells
Published on: August 19, 2016
RELATION BETWEEN THE VIRULENCE OF STREPTOCOCCI AND HEMOLYSIN
F A Stevens1, J W Brady, R West
1Medical Clinic of the Presbyterian Hospital, Columbia University, New York.
Abstract:
Strains of streptococci whose virulence has been increased for any one species of animal do not produce greater concentrations of hemolysin than the original strain. Furthermore, there is a tendency for the original culture to grow more rapidly than the more pathogenic form, and to reach the height of hemolysin production at an earlier stage during the growth of the culture. These conclusions can probably be applied only to experiments in which the serum used in the media is from some species not employed for the animal passages.
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