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Updated: Jun 19, 2026

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates
Published on: May 30, 2017
MUTATION AMONG HOG-CHOLERA BACILLI
1Department of Animal Pathology of The Rockefeller Institute for Medical Research, Princeton, N. J.
Abstract:
1. In the hog-cholera group the mutation from smooth (A) to granular (B) type occurs and a mutant with a moist, opaque colony formation was noted. 2. The B mutant when obtained pure remains a B type without reversion in the stock cultures. 3. The B mutant can be made to assume some of the A characters by rapid successive transplanting in bouillon. 4. The B mutant can usually be found in older transplants of A. 5. The two types may be distinguished by certain cultural characters, by slightly different agglutination reactions, and by different degrees of virulence.
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