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Published on: November 6, 2020
RISE IN TEMPERATURE PRECEDING THE APPEARANCE OF SYMPTOMS IN EXPERIMENTAL POLIOMYELITIS
S D Kramer1, K H Hendrie, W L Aycock
1Department of Preventive Medicine and Hygiene, Harvard University Medical School, Boston, and the Research Laboratory of the Vermont Department of Public Health, Burlington.
Abstract:
The data presented in this paper offer a means of earlier recognition of experimental poliomyelitis in the monkey. The early appearance of the temperature rise (1 to 3 days before the onset of the usual recognizable symptoms) associated with spinal fluid changes suggests that there is a stage in the experimental disease corresponding to preparalytic human poliomyelitis.
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