Related Experiment Video
Updated: Jun 19, 2026

Particle Agglutination Method for Poliovirus Identification
Published on: April 20, 2011
IMMUNITY TO POLIOMYELITIS IN MOTHERS AND THE NEWBORN AS SHOWN BY THE NEUTRALIZATION TEST
1Department of Preventive Medicine and Hygiene, Harvard Medical School, Boston, and the Research Laboratory of the Vermont Department of Public Health, Burlington.
Abstract:
Neutralization tests for the virus of poliomyelitis on blood serum of urban mothers and their newborn infants showed that immunity was present in ten out of twelve (83 per cent) infants and in ten out of twelve (83 per cent) mothers, with a complete correspondence between mother and infant. These tests point to passive transmission of immunity from mother to infant. Previous tests on other children (1 to 5 years) indicate that immunity in infants is transitory. Previous observations concerning the extent of immunity in urban adults are confirmed and extended. The results of these tests are in accord with the age distribution of poliomyelitis and parallel corresponding observations in diphtheria.
More Related Videos
12:09Measuring Influenza Neutralizing Antibody Responses to A(H3N2) Viruses in Human Sera by Microneutralization Assays Using MDCK-SIAT1 Cells
Published on: November 22, 2017
07:13Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic Poly(I:C)
Published on: March 25, 2016
Related Concept Videos
Poliomyelitis
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Immunological Memory
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...
Active versus Passive Immunity
Active Immunity
Active immunity refers to the resistance one develops...
Diphtheria
Cytomegalovirus Disease