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Updated: Jun 19, 2026

Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092
Published on: October 2, 2017
SPECIFIC AND NON-SPECIFIC POLYSACCHARIDES OF TYPE IV PNEUMOCOCCUS
1Department of Medicine, College of Physicians and Surgeons, Columbia University, and the Presbyterian Hospital, New York.
Abstract:
1. Three nitrogen-containing polysaccharides have been isolated from autolyzed cultures of Type IV pneumococcus: (1) a type-specific carbohydrate differing markedly from those of Type I, II, and III pneumococcus, and representing a type of substance hitherto not observed among specific polysaccharides, (2) a chemically similar carbohydrate without specific function, and (3) the "C" substance, or species-specific polysaccharide of Tillett, Goebel, and Avery. 2. The chemical differences between the specific polysaccharides of Pneumococcus are discussed, and the relationship of the new examples to chitin is pointed out and its bearing indicated on the unsettled controversy as to whether or not chitin occurs in bacteria. 3. The data of Tillett, Goebel, and Avery on the "C" substance have been extended.
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