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Updated: Jun 19, 2026

Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling
Published on: February 5, 2018
CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : VI. THE SYNTHESIS OFp-AMINOPHENOLalpha-GLUCOSIDE
W F Goebel1, F H Babers, O T Avery
1Hospital of The Rockefeller Institute for Medical Research.
Abstract:
1. The synthesis of p-aminophenol alpha-glucoside has been described. This glucoside can be coupled to any protein to yield a synthetic alpha-glucoside-protein complex. 2. A synthetic beta-glucoside-protein complex has also been prepared. 3. These synthetic sugar-protein complexes have been used as immunizing antigens in order to ascertain whether alpha- and beta-glucosidic unions influence the specificity of the immune response in animals. The results of the immunological studies are presented in the following paper.
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