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THE DETECTION OF POLIOMYELITIS VIRUS IN SO CALLED ABORTIVE TYPES OF THE DISEASE

J R Paul1, J D Trask

  • 1Departments of Medicine and Pediatrics, Yale University, New Haven.

The Journal of Experimental Medicine
|October 30, 2009
PubMed

Insights

Poliomyelitis virus was isolated from patients with minor illnesses, suggesting these are mild cases. This provides evidence that characteristic minor illnesses during an epidemic are likely mild poliomyelitis.

Area of Science:

  • Virology
  • Epidemiology
  • Infectious Diseases

Background:

  • Poliomyelitis is a serious infectious disease.
  • Minor illnesses often accompany poliomyelitis epidemics.
  • The nature of these minor illnesses has been debated.

Purpose of the Study:

  • To investigate the relationship between minor illnesses and poliomyelitis.
  • To determine if poliomyelitis virus can be isolated from patients with minor illnesses.

Main Methods:

  • Isolation of poliomyelitis virus from throat swabs.
  • Clinical observation of patients with minor illnesses during a poliomyelitis epidemic.

Main Results:

  • Poliomyelitis virus was successfully isolated from the throats of two patients presenting with minor illnesses.
  • These patients experienced characteristic minor illnesses, termed "abortive poliomyelitis" (Wickman type).

Conclusions:

  • The isolation of poliomyelitis virus supports the hypothesis that minor illnesses during an epidemic are mild cases of the disease.
  • This finding strengthens the understanding of poliomyelitis transmission and presentation.

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