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Published on: November 30, 2015
A QUANTITATIVE TECHNIQUE FOR PERFORMING PLASMAPHERESIS.
1Laboratory of Physiological Chemistry, Yale University, New Haven.
The Journal of Experimental Medicine
|October 30, 2009
Summary
This study introduces a new apparatus and technique for precise quantitative plasmapheresis. It validates methods for calculating blood volume and serum protein concentration needed for safe blood withdrawal.
Area of Science:
- Biomedical Engineering
- Clinical Pathology
- Hematology
Background:
- Plasmapheresis requires accurate blood volume and serum protein measurements.
- Existing methods may lack precision for quantitative procedures.
Purpose of the Study:
- To describe a novel apparatus and technique for quantitative plasmapheresis.
- To validate methods for determining essential parameters for plasmapheresis procedures.
Main Methods:
- Development of a specialized apparatus for quantitative plasmapheresis.
- Application of validated techniques for serum protein concentration determination.
- Calculation of blood volume for precise blood withdrawal.
Main Results:
- The described apparatus and technique enable quantitative plasmapheresis.
- Validated methods ensure accurate determination of serum protein and blood volume.
- Precise calculation of blood to be withdrawn is achievable.
Conclusions:
- The novel apparatus and technique offer a reliable method for quantitative plasmapheresis.
- Accurate prerequisite measurements are crucial for the safety and efficacy of plasmapheresis.
- This methodology enhances the precision of therapeutic plasma exchange procedures.
