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Updated: Jun 19, 2026

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope
Published on: March 24, 2017
ON THE SEROLOGICAL SPECIFICITY OF PEPTIDES. III
K Landsteiner1, J van der Scheer
1Laboratories of The Rockefeller Institute for Medical Research.
Abstract:
Experiments are described dealing with immune sera to pentapeptides and peptide amides. Absorption and inhibition tests gave no indication of the presence in the immune sera of special antibodies for portions of a peptide molecule but the antibodies appeared to be specific for an entire pentapeptide even though the sera contained qualitatively different fractions. Marked disparity was found between the reactions of peptides and corresponding amides indicating differences between acid and other polar groups in their influence on serological specificity.
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