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Updated: Jun 19, 2026

High Yield Purification of Plasmodium falciparum Merozoites For Use in Opsonizing Antibody Assays
Published on: July 17, 2014
PRODUCTION IN MONKEYS OF COMPLEMENT-FIXING ANTIBODIES WITHOUT ACTIVE IMMUNITY BY INJECTION OF KILLED PLASMODIUM
1Laboratories of the International Health Division of The Rockefeller Foundation, New York.
Abstract:
Injection into rhesus monkeys of Plasmodium knowlesi killed by heat, formalin, drying, or freezing and thawing stimulates the production of complement-fixing antibodies, but no demonstrable agglutinating or protective antibodies are formed. Possible differences in the immunity mechanisms concerned in active infection and in artificial immunization are discussed.
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