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Updated: Jun 19, 2026

Erythrocyte Sedimentation Rate: A Physics-Driven Characterization in a Medical Context
Published on: March 24, 2023
A COMPARISON OF ERYTHROCYTE SEDIMENTATION RATES AND ELECTROPHORETIC PATTERNS OF NORMAL AND PATHOLOGICAL HUMAN BLOOD
1Laboratories of The Rockefeller Institute for Medical Research.
Electrophoretic studies and erythrocyte sedimentation rate measurements were carried out on normal and pathological human blood. An increase in alpha globulin levels appears to take place, as well as an increase in sedimentation rates, when there is present any considerable inflammation or tissue destruction, irrespective of its cause. A graphic correlation is presented between sedimentation rates and alpha globulin levels, which is at least as good as a similar correlation involving fibrinogen levels.
Electrophoretic studies and erythrocyte sedimentation rate measurements were carried out on normal and pathological human blood. An increase in alpha globulin levels appears to take place, as well as an increase in sedimentation rates, when there is present any considerable inflammation or tissue destruction, irrespective of its cause. A graphic correlation is presented between sedimentation rates and alpha globulin levels, which is at least as good as a similar correlation involving fibrinogen levels.
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