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Updated: Jun 19, 2026

Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications
Published on: August 4, 2017
THE EFFECT OF HYDROGEN ION CONCENTRATION ON SWELLING OF CELLS
1Laboratory of Pathology, School of Medicine, University of Pennsylvania, Philadelphia, and the Marine Biological Laboratory, Woods Hole.
Abstract:
1. The effect of HCl, NaOH, CO(2), and NH(3) on the volume of unfertilized Arbacia eggs was tested over a wide range of pH values. 2. No swelling occurred, except in HCl solutions, and there not until after injury or death had occurred. 3. Whereas the volume of erythrocytes and of proteins such as gelatin is known to be dependent on the pH of the solution, such a relation does not exist in the case of living and uninjured cells, at least of the type tested.
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