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A METHOD FOR THE QUANTITATIVE DETERMINATION OF BACTERIOPHAGE

A P Krueger1

  • 1Laboratories of The Rockefeller Institute for Medical Research, Princeton, N. J.

The Journal of General Physiology
|October 30, 2009
PubMed

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Bacteriophages, also known as phages, are specialized viruses that infect bacteria. A key characteristic of phages is their distinctive “head-tail” morphology. A phage begins the infection process (i.e., lytic cycle) by attaching to the outside of a bacterial cell. Attachment is accomplished via proteins in the phage tail that bind to specific receptor proteins on the outer surface of the bacterium. The tail injects the phage’s DNA genome into the bacterial cytoplasm. In the lytic replication...