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Metabolic Labeling of Leucine Rich Repeat Kinases 1 and 2 with Radioactive Phosphate
Published on: September 18, 2013
The uptake of a labeled double-stranded polynucleotide by cultured rabbit kidney cells: an electron microscopic study
P H Prose1, A Friedman-Kien, J Vilcek
1Departments of Pathology, Dermatology, and Virology, New York University School of Medicine, New York 10016.
The Journal of General Physiology
|October 30, 2009
Abstract:
Polyribocytidylate-(3)H-polyriboinosinate (rC-(3)H:rI) enters cultured rabbit kidney cells from the surrounding medium within (1/2) hr after exposure. Grains are found in the cytoplasm, nucleus, and nucleolus. At 2 hr, grains are localized predominantly over the nucleolar regions. Subsequently, the grains in the nucleus become dispersed. A specific receptor site for the initiation of interferon production was not revealed.
