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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: Jun 19, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

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Published on: May 25, 2020

Assessment of the Student Sight Savers Program methods for glaucoma screening.

Sarwat Salim1, Peter A Netland, Kenneth H Fung

  • 1Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.

Ophthalmic Epidemiology
|October 31, 2009
PubMed
Summary

Frequency Doubling Technology (FDT) visual field testing showed high specificity for glaucoma screening in the Student Sight Savers Program. While FDT performed best individually, combining screening methods increased sensitivity but reduced overall specificity.

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Area of Science:

  • Ophthalmology
  • Public Health
  • Screening Technologies

Background:

  • The Student Sight Savers Program (SSSP) has been screening for glaucoma in the United States since 2001.
  • Assessing the effectiveness of screening methods is crucial for early glaucoma detection and intervention.

Purpose of the Study:

  • To evaluate the efficacy of different glaucoma screening methods employed by the SSSP.
  • To determine the sensitivity, specificity, and positive predictive power of individual and combined screening tests.

Main Methods:

  • A prospective, case-control, clinic-based study involving 70 participants.
  • Patients with primary open-angle glaucoma and matched controls were assessed using SSSP screening methods.
  • Primary outcomes included sensitivity, specificity, and positive predictive power in low- and high-prevalence populations.

Main Results:

  • Frequency Doubling Technology (FDT) visual field testing demonstrated high specificity (98.6%) but moderate sensitivity (58.1%).
  • Individual test performance: family history (48.6% sensitivity, 68.6% specificity), intraocular pressure (IOP) (22.1% sensitivity, 78.6% specificity).
  • Combined screening criteria increased sensitivity to 88.6% but decreased specificity to 57.1%; FDT yielded the highest positive predictive power.

Conclusions:

  • Frequency Doubling Technology (FDT) is the most effective single screening test for glaucoma within the SSSP, offering high specificity.
  • Employing multiple screening criteria enhances sensitivity and positive predictive power but compromises specificity.
  • Further assessment of the program's educational and community awareness components is needed.