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Updated: Jun 19, 2026
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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Prevalence and risk factors related to infections of cardiac resynchronization therapy devices
Cécile Romeyer-Bouchard1, Antoine Da Costa, Virginie Dauphinot
1Division of Cardiology, University Jean Monnet of Saint-Etienne, Saint-Etienne 42000, France.
European Heart Journal
|October 31, 2009
Summary
Device-related infections (DRI) affect 4.3% of patients with cardiac resynchronization therapy (CRT) devices. Key predictors include longer procedure times, dialysis, re-intervention, and CRT-ICD implantation.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Devices
Background:
- Device-related infections (DRI) are a significant complication following cardiac resynchronization therapy (CRT) implantation.
- Understanding the prevalence and predictors of CRT DRI is crucial for patient management.
Purpose of the Study:
- To determine the prevalence of DRI in patients with CRT devices.
- To identify factors that predict the occurrence of CRT DRI.
Main Methods:
- A retrospective analysis of 303 patients who underwent CRT implantation between 2001 and 2007.
- Univariate and multivariate analyses were performed to identify predictive factors for DRI.
Main Results:
- The overall prevalence of CRT DRI was 4.3%, with endocarditis, pocket erosion, and pocket abscess being the most common types.
- Independent predictors of DRI included longer procedure time, need for dialysis, re-intervention, and initial implantation of a CRT-ICD system.
Conclusions:
- The incidence of CRT DRI is approximately 1.7% per year.
- Identifying patients at higher risk based on procedure time, dialysis status, re-intervention history, and device type can inform pre-operative risk-benefit assessments.
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