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Updated: Jun 19, 2026

Creating Transient Cell Membrane Pores Using a Standard Inkjet Printer

Creating Transient Cell Membrane Pores Using a Standard Inkjet Printer

Published on: March 16, 2012

Biosurface engineering through ink jet printing.

Mohidus Samad Khan¹, Deniece Fon, Xu Li

¹Australian Pulp and Paper Institute, Department of Chemical Engineering, Monash University, Clayton, VIC 3800, Australia.

Colloids and Surfaces. B, Biointerfaces

|November 3, 2009

Summary

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Thermal ink jet printing is a viable method for biosurface engineering. This technique allows for precise printing of proteins and enzymes on various materials for applications in tissue regeneration and diagnostics.

Area of Science:

Biotechnology
Materials Science
Surface Engineering

Background:

Biosurface engineering requires precise deposition of biomolecules.
Traditional methods may struggle with resolution and biomolecule integrity.
Thermal ink jet printing offers potential for high-resolution biofabrication.

Purpose of the Study:

To demonstrate the feasibility of thermal ink jet printing for biosurface engineering.
To optimize bio-ink properties for high-resolution printing.
To assess the impact of printing on protein and enzyme stability.

Main Methods:

Commercial thermal ink jet printer reconstruction and modification.
Formulation of bio-inks with specific viscosity and surface tension.

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Last Updated: Jun 19, 2026

Creating Transient Cell Membrane Pores Using a Standard Inkjet Printer

Creating Transient Cell Membrane Pores Using a Standard Inkjet Printer

Published on: March 16, 2012

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Printing of protein and enzyme concentration gradients on scaffolds.

Assessment of biomolecule stability post-printing.

Evaluation of printed protein desorption and enzyme activity.

Main Results:

High-resolution printing of biomolecules was achieved.
Thermal ink jet printing caused insignificant protein and enzyme denaturation.
Printed proteins exhibited stability upon prolonged aqueous immersion.
Complex biopatterns were successfully printed on large areas.
Enzyme patterns were printed for paper-based diagnostics.

Conclusions:

Thermal ink jet printing is a robust and versatile technique for biosurface engineering.
The method preserves biomolecule integrity, enabling applications in tissue engineering and diagnostics.
Printed scaffolds are suitable for both in vitro and in vivo use.