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WITHDRAWN: NOX5 participates in the oxidative damage caused by fluoride in rat spermatozoa, and alpha-Tocopherol

Jeannett A Izquierdo-Vega1, Manuel Sánchez-Gutiérrez, Luz María Del Razo

  • 1Toxicología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), México, DF 07360, Mexico.

Toxicology Letters
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Oxidation of Phenols to Quinones01:17

Oxidation of Phenols to Quinones

In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox property is crucial in...