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Updated: Jun 19, 2026
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Spitzoid melanoma
1Dermatopathology Section, Department of Dermatology, New York University School of Medicine, 530 First Avenue, Suite 7J, New York, NY 10016, USA. hideko.kamino@nyu.org
Abstract:
Because spitzoid melanoma shares many histopathologic features with Spitz nevus, it is one of the most difficult lesions to diagnose in dermatopathology. Uncertainty exists in the medical literature about how to diagnose melanocytic proliferations including Spitz nevus and spitzoid melanoma. A misdiagnosis of a melanoma as Spitz nevus is one of the most frequent causes of malpractice lawsuits in surgical pathology and dermatopathology. This contribution provides a review of the clinical presentation, histopathology, ancillary studies, treatment, and the differential diagnosis of spitzoid melanoma.
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