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The effect of clinical severity and eyelid rash on ocular involvement in primary varicella infection

Gulten Sungur1, Dicle Hazirolan, Serkan Duran

  • 1Department of 1st Eye Clinic, Ankara Training and Research Hospital, Ministry of Health, Ankara - Turkey.

European Journal of Ophthalmology
|November 3, 2009
PubMed

Insights

Ocular manifestations in primary varicella infection are common but not linked to disease severity or eyelid rash. Pediatricians should refer patients with ocular symptoms for examination, as prognosis is generally good.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Infectious Diseases

Background:

  • Primary varicella infection (chickenpox) can present with various clinical manifestations.
  • Ocular involvement in varicella is a recognized complication, but its association with systemic severity and specific dermatological signs requires further clarification.

Purpose of the Study:

  • To investigate the occurrence of ocular manifestations in children with primary varicella infection.
  • To determine the relationship between ocular involvement, systemic varicella severity, and the presence of an eyelid rash.

Main Methods:

  • Prospective examination of 100 children with primary varicella.
  • Classification of varicella cases into mild, moderate, and severe based on clinical presentation.
  • Grouping of patients based on the presence (G1) or absence (G2) of ocular findings, excluding eyelid rash.

Main Results:

  • Twenty-one percent of children experienced ocular involvement.
  • Conjunctivitis (38.1%), anterior uveitis (57.1%), and disciform keratouveitis (4.8%) were the primary ocular findings.
  • No significant association was found between varicella severity and ocular involvement (p=0.712) or between eyelid rash and ocular involvement (p=0.787).

Conclusions:

  • The severity of primary varicella infection is not associated with the severity of ocular involvement.
  • The presence of a varicella eyelid rash does not correlate with the development of uveitis.
  • Referral for ophthalmologic examination is recommended for pediatric patients presenting with ocular signs and symptoms of varicella, given the favorable prognosis for ocular sequelae.
Abstract

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