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Solid Phase Synthesis of a Functionalized Bis-Peptide Using "Safety Catch" Methodology
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Published on: May 15, 2012

Solvent-free synthesis of peptides

Valérie Declerck1, Pierrick Nun, Jean Martinez

  • 1Institut des Biomolécules Max Mousseron, UMR 5247 CNRS-UM1-UM2, Université Montpellier II, Place Eugène Bataillon, 34095 Montpellier Cedex 5, France.

Angewandte Chemie (International Ed. in English)
|November 3, 2009
PubMed
Abstract

No abstract available in PubMed .

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Peptide Bonds02:43

Peptide Bonds

A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...

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