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Updated: Jun 19, 2026

Synovial Fluid Analysis to Identify Osteoarthritis
Published on: October 20, 2022
[Infrared spectroscopy of synovial fluid and serum from patients with joint diseases]
Abstract:
The infrared spectra of synovial fluid and serum from the same patient were comparatively analyzed. The coordination bond variations in the complex protein-polysaccharide compounds of synovial fluid were shown to correspond to the range of frequencies of 3000-3500 cm(-1) and those of valence bonds in its individual components were in the range of 800-1700 cm(-1). It was established that a reduction in the peak area of 3300 cm(-1) may be an additional indicator in the diagnosis of osteoarthritis. The above results confirm it expedient to treat joints, by injecting serum-based agents.
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