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Published on: May 16, 2019
[Evolution of assisted reproductive technologies].
1Laboratoire de Biologie de la Reproduction-CECOS, Hôpital Cochin, Université Paris Descartes.
Bulletin De L'Academie Nationale De Medecine
|November 4, 2009
Summary
Assisted reproductive technologies (ART) have evolved significantly, from artificial insemination to in vitro fertilization (IVF) and genetic screening. These advancements offer new pathways for parenthood and address infertility challenges.
Area of Science:
- Reproductive Biology
- Genetics
- Medical Technology
Context:
- Human reproduction historically relied on natural conception.
- Medical interventions began in the 18th century with artificial insemination.
- Technological advancements in the 20th and 21st centuries revolutionized reproductive possibilities.
Purpose:
- To explore the historical evolution and technological advancements in assisted reproductive technologies (ART).
- To examine the impact of ART on overcoming infertility and redefining parenthood.
- To discuss the societal implications and ethical considerations of modern reproductive medicine.
Summary:
- ART encompasses techniques like artificial insemination, donor sperm, gamete freezing, in vitro fertilization (IVF), and intracytoplasmic sperm injection (ICSI).
- Recent advancements include preimplantation genetic screening to prevent the birth of children with genetic disorders.
- ART now extends options to single individuals and same-sex couples, challenging traditional notions of family.
Impact:
- ART provides alternatives for individuals and couples facing infertility.
- These technologies enable the prevention of certain genetic and chromosomal abnormalities.
- ART is reshaping societal views on reproduction, parenthood, and family structures, presenting new ethical and legal discussions.
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Reproductive Cloning
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In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic cell—any cell that is not a sex...
Somatic Cell Nuclear Transfer
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Reproductive Cloning
Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic cell—any cell that is not a sex...
Somatic Cell Nuclear Transfer
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Cloning of Dolly the Sheep
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Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced Short...

