Related Experiment Video

Updated: Jun 25, 2025

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
06:11

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

Published on: May 17, 2024

595

[Medium and long-term health outcome of children conceived through in vitro fertilization]

Pierre Jouannet1, Olivier Claris2, Yves Le Bouc3

  • 1Université Paris Sorbonne, Paris, France.

La Revue Du Praticien
|May 30, 2024
PubMed

Insights

Children conceived via in vitro fertilization (IVF) may experience health issues, but the incidence is moderate and comparable to naturally conceived children. Underlying causes for these health outcomes require further investigation.

Area of Science:

  • Reproductive Medicine
  • Pediatric Health
  • Genetics

Background:

  • In vitro fertilization (IVF) is a common assisted reproductive technology.
  • Concerns exist regarding the long-term health of children conceived through IVF.
  • Previous studies have investigated various health outcomes in this population.

Purpose of the Study:

  • To evaluate the medium and long-term health outcomes of children conceived via IVF.
  • To compare the incidence of health problems in IVF-conceived children with naturally conceived children.
  • To explore potential contributing factors to observed health alterations.

Main Methods:

  • Review of numerous existing studies on IVF-conceived children's health.
  • Analysis of reported health alterations and their prevalence.
  • Consideration of parental infertility as a potential confounding factor.

Main Results:

  • Children conceived via IVF may experience health problems, but the overall incidence is moderate.
  • The rate of health issues in IVF-conceived children is not significantly higher than in naturally conceived children.
  • Observed alterations are not solely attributable to IVF; parental factors may play a role.

Conclusions:

  • The health risks for children conceived through IVF appear to be relatively low and comparable to natural conception.
  • Parental infertility may contribute to certain health disturbances in offspring, independent of conception method.
  • Further research is needed to elucidate the mechanisms, such as epigenetic disruptions, underlying observed health outcomes.

Keywords:
Child HealthFertilization in Vitro

More Related Videos

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery05:31

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery

Published on: May 9, 2021

4.0K
Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives08:46

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

5.9K

Related Concept Videos

In Vitro Fertilization01:24

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
247
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
260
Birth Control Methods01:22

Birth Control Methods

Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
230
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K
Infertility in Females01:28

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
292
Meiosis II01:57

Meiosis II

Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each...
183.3K