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Real-time 2-D temperature imaging using ultrasound.

Dalong Liu¹, Emad S Ebbini

¹Department of Biomedical Engineering, University of Minnesota,Minneapolis, MN 55455, USA. liuxx293@umn.edu

IEEE Transactions on Bio-Medical Engineering

|November 4, 2009

Summary

This study introduces a real-time ultrasound system for 2-D temperature imaging, enhancing minimally invasive thermal therapies. The system accurately monitors temperature changes during procedures like high-intensity-focused ultrasound (HIFU).

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Area of Science:

Medical Imaging
Biomedical Engineering
Ultrasound Technology

Background:

Noninvasive temperature estimation using diagnostic ultrasound has been validated but faces limitations for thermal therapy guidance.
Existing methods struggle with real-time monitoring and guidance for minimally invasive thermal therapies such as radiofrequency ablation and high-intensity-focused ultrasound (HIFU).

Purpose of the Study:

To present the first results from a real-time 2-D temperature imaging system using pulse-echo ultrasound.
To overcome limitations of previous ultrasound-based thermometry for guiding thermal therapies.

Main Methods:

Utilized a commercial ultrasound scanner with a research interface for real-time RF data access.
Employed a high-frame-rate 2-D RF acquisition mode (M2D) to capture tissue motion during pulsed HIFU.
Developed a 2-D temperature imaging algorithm based on speckle tracking, implemented on a GPU for real-time processing.

Main Results:

Demonstrated repeatability and sensitivity in monitoring HIFU-induced heating of an elastography phantom.
Showcased in vitro results indicating the algorithm's capability to image tissue parameter changes from HIFU-induced lesions.
Verified real-time data streaming and processing for effective monitoring.

Conclusions:

The developed real-time 2-D ultrasound temperature imaging system shows significant value for monitoring and guidance of minimally invasive thermotherapies.
The system's ability to provide real-time temperature change images is crucial for improving the safety and efficacy of thermal ablation procedures.
This technology advances the application of ultrasound in guiding thermal therapies by offering accurate and immediate feedback.