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Effect of early intervention on 8-year growth status of low-birth-weight preterm infants
Patrick H Casey1, Robert H Bradley, Leanne Whiteside-Mansell
1Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA. caseypatrickh@uams.edu
Insights
Early educational intervention improved growth in preterm infants. Children who received the Infant Health and Development Program intervention showed increased height and head circumference by age 8.
Area of Science:
- Pediatric Growth and Development
- Early Childhood Education Impact
- Developmental Pediatrics
Background:
- The Infant Health and Development Program (IHDP) demonstrated positive effects on intelligence and adaptive functioning in preterm infants up to age 8.
- Understanding the long-term effects of early educational interventions on physical growth is crucial for child development research.
Purpose of the Study:
- To evaluate the impact of an early educational intervention on the growth status of children at age 8 years.
- To determine if the IHDP's educational component influences physical growth parameters in preterm infants.
Main Methods:
- A randomized controlled trial involving home and center-based educational interventions.
- Participants included 377 intervention (INT) and 608 non-intervention (NI) children, stratified by birth weight (2001-2500g and <=2000g).
- Educational intervention was provided from nursery discharge until age 3 years, with growth outcomes assessed at age 8.
Main Results:
- At age 8, intervention children were significantly taller (127.6 vs 126.6 cm) and had larger head circumferences (52.5 vs 52.1 cm) compared to non-intervention children.
- Overweight and underweight prevalence was similar between groups (9% and 4.5%, respectively).
- Lighter low-birth-weight intervention children exhibited greater weight (28.0 vs 26.8 kg), head circumference (52.6 vs 52.1 cm), and height (127.6 vs 126.5 cm) than their non-intervention counterparts.
Conclusions:
- The IHDP educational intervention positively impacted the physical growth of low-birth-weight preterm children, particularly the lighter low-birth-weight group.
- Children receiving the intervention demonstrated enhanced growth in terms of weight, height, and head circumference by age 8.
- Early educational experiences can have lasting effects on physical development in vulnerable preterm populations.
Objective:
To examine the impact of early educational experience at age 8 years on child growth status. The Infant Health and Development Program has shown positive impacts to age 8 years on intelligence and adaptive functioning of larger preterm infants.
Design:
Randomized controlled trial.
Setting:
Home and center based.
Participants:
Three hundred seventy-seven intervention (INT) and 608 nonintervention (NI) children, stratified by birth-weight categories 2001 to 2500 g and 2000 g or less. Intervention Educational intervention from nursery discharge until age 3 years.
Main Outcome Measures:
Eight-year weight, height, head circumference, and body mass index.
Results:
Complete data were available for 313 INT children and 491 NI children. Adjusting for child birth weight, birth-weight category, treatment group x birth-weight category interaction, sex, race, and Neonatal Health Index; maternal education and preconception weight; and site, the INT children at age 8 years were significantly taller (127.6 vs 126.6 cm; P = .02) and had a larger head circumference (52.5 vs 52.1 cm; P < .001) than the NI children. The prevalence of both overweight (9%) and underweight (4.5%) was the same in both treatment groups. Lighter low-birth-weight INT children had greater 8-year weight (28.0 vs 26.8 kg; P = .02), larger head circumference (52.6 vs 52.1 cm; P < .001), and larger height (127.6 vs 126.5 cm; P = .05) compared with their counterparts in the NI group.
Conclusion:
Low-birth-weight preterm children, specifically the lighter low-birth-weight group, who received the Infant Health and Development Program educational intervention were heavier and taller and had greater head circumference compared with NI children in the same birth-weight category.
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