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Updated: Jun 19, 2026

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Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
Published on: March 25, 2019
SERS detection and boron delivery to cancer cells using carborane labelled nanoparticles
David C Kennedy1, Dominique R Duguay, Li-Lin Tay
1Steacie Institute for Molecular Sciences, National Research Council Canada, 100 Sussex Drive, Ottawa, Canada K1A 0R6.
Abstract:
Water-soluble carborane functionalized nanoparticles also co-functionalized with targeting antibodies have been prepared. We demonstrate tumour cell targeting with anti-EGFR antibodies and delivery of a high concentration of boron using SERS imaging. This suggests these materials have a therapeutic potential in addition to multimodal imaging capabilities.

