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Updated: Jun 19, 2026
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Published on: April 18, 2011
Functional assessment of lower extremities in hereditary spastic paraplegia
Mark Braschinsky1, Kadri Parts, Heigo Maamägi
1Tartu University, Department of Neurology, 8 L. Puusepp St, Tartu, 51014, Estonia. mark.braschinsky@kliinikum.ee
Objectives:
To characterize the spasticity and range of motion (ROM) in patients with hereditary spastic paraplegia (HSP) and to correlate these parameters with walking speed.
Design:
An observational population-based cohort study.
Setting:
Patient data were acquired from a population-based epidemiologic study performed earlier in Estonia.
Participants:
Persons (N=46) (mean age, 50.1y) with clinically confirmed HSP diagnosis (mean duration, 20.9y) participated in the study.
Interventions:
Active and passive ROMs were measured with a plastic 360 degrees goniometer. Spasticity was evaluated by using the modified Ashworth scale (MAS). The time it took a patient to walk 10m was recorded.
Main Outcome Measures:
Measurements included testing of active and passive ROM as a marker for mobility, the MAS for spasticity, and time to complete a 10-m walk.
Results:
A higher degree of spasticity in hip muscles was associated with lower values of active ROM and slower walking. Walking speed was negatively correlated to disease duration and participant age.
Conclusions:
The present study provides analysis of the contributions of spasticity and ROM to walking speed in HSP, both factors negatively influence gait in persons with HSP.
