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Updated: Jun 19, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Abstract:
Low mood associated with a certain season (usually winter) is very common. For example, in the UK, up to 6% of adults have "recurrent major depressive episodes with seasonal pattern", commonly known as seasonal affective disorder (SAD). People with SAD consult in primary care more often than age- and gender-matched control groups; patients also receive more prescriptions and are referred more often to secondary care. Around 6-35% of patients require hospitalisation for SAD at some point.5 Here we discuss the management of adults with SAD, and in particular light therapy.
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