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High celecoxib-loaded nanoparticles prepared by a vibrating nozzle device

Alenka Zvonar1, Julijana Kristl, Janez Kerc

  • 1Faculty of Pharmacy, University of Ljubljana, 1000 Ljubljana, Slovenia.

Journal of Microencapsulation
|November 6, 2009
PubMed
Summary

This study demonstrates a vibrating nozzle device for creating celecoxib nanoparticles (NP) using polylactic acid (PLA) and poly(lactic-co-glycolic acid) (PLGA). The method yields reproducible, stable nanoparticles with high drug loading and sustained release for improved drug delivery.

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