Related Experiment Video
Updated: Jun 19, 2026

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
Spontaneous rupture of primigravid uterus due to morbidly adherent placenta
Afia Ansar1, Nosheen Rauf, Khadija Bano
1Department of Obstetrics and Gynaeocology, Jinnah Postgraduate Medical Centre, Karachi. afiajpmc@yahoo.com
Morbidly adherent placenta in a nulliparous woman is a rare phenomenon. An unusual case of a 20 years old primigravida presented in emergency with unstable haemodynamics and abdominal pain at 17 weeks of gestation is reported. She was found to have complete placental invasion and haemoperitoneum on laparotomy. Although there is an increased risk of placental invasion (increta and percreta) causing uterine rupture in previous cesareans but morbid adhesion resulting in placenta percreta without previous uterine surgery is a rarity. Exact pathogenesis is still unknown. Prenatal diagnosis with the help of Doppler ultrasound and MRI is important to reduce both fetal and maternal morbidity and mortality.
Morbidly adherent placenta in a nulliparous woman is a rare phenomenon. An unusual case of a 20 years old primigravida presented in emergency with unstable haemodynamics and abdominal pain at 17 weeks of gestation is reported. She was found to have complete placental invasion and haemoperitoneum on laparotomy. Although there is an increased risk of placental invasion (increta and percreta) causing uterine rupture in previous cesareans but morbid adhesion resulting in placenta percreta without previous uterine surgery is a rarity. Exact pathogenesis is still unknown. Prenatal diagnosis with the help of Doppler ultrasound and MRI is important to reduce both fetal and maternal morbidity and mortality.
Related Concept Videos
Mitral Valve Prolapse III: Nursing Management
Mitral Valve Prolapse I: Introduction
Intestinal Obstruction II: Pathophysiology
Disorders of the Female Reproductive System
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Menses Phase
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...

