Related Experiment Video
Updated: Jun 19, 2026
09:44
Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Keratitis-ichthyosis-deafness (KID) syndrome.
Mercedes E Gonzalez1, Brook E Tlougan, Harper N Price
1Department of Dermatology, New York University, USA.
Dermatology Online Journal
|November 7, 2009
Summary
Keratitis-ichthyosis-deafness (KID) syndrome presents with skin, hearing, and eye issues. This case highlights scalp infections and cysts as potential KID syndrome manifestations, emphasizing cancer risks.
Area of Science:
- Dermatology
- Genetics
- Otolaryngology
Background:
- Keratitis-ichthyosis-deafness (KID) syndrome is a rare genetic disorder.
- It is characterized by a triad of ocular, cutaneous, and auditory abnormalities.
Observation:
- A 21-year-old male presented with congenital skin anomalies including diffuse skin thickening, verrucous plaques, and palmoplantar keratoderma.
- The patient also exhibited sensorineural hearing loss and keratoconjunctivitis, consistent with KID syndrome.
- He reported a history of recurrent scalp infections, cysts, and inflammatory nodules.
Findings:
- This case underscores scalp manifestations such as folliculitis, cysts, and recurrent infections as potential features of KID syndrome.
- The study highlights the association between KID syndrome and an increased risk of follicular tumors and squamous-cell carcinomas.
Implications:
- Early recognition of diverse KID syndrome presentations, including scalp issues, is crucial for timely management.
- Increased awareness of oncological risks in KID syndrome patients is warranted for proactive surveillance and treatment.
Related Concept Videos
01:33Pleiotropy
Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
00:50Unrenewable Cells
In humans, the photoreceptor cells of the eye and sensory hair cells of the ear lack stem cells. These cells are thus unrenewable and cannot be replaced when they are damaged or destroyed.
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of their outer...
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of their outer...
01:22Photoreceptors and Visual Pathways
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
01:24Chronic Kidney Disease II: Clinical Manifestations
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
01:19Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
01:31Hearing
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.