Related Experiment Video
Updated: Jun 18, 2026

Cultivation Methods of Spirochetes from Borrelia burgdorferi Sensu Lato Complex and Relapsing Fever Borrelia
Published on: November 25, 2022
Borrelia burgdorferi, a great chameleon: know it to recognize it!
Iolanda Santino1, Paola Comite, Giuseppe Maria Gandolfo
1Department of Public Health Sciences, Sapienza University of Rome, Rome, Italy. iolanda.santino@uniroma1.it
Abstract:
Borrelia burgdorferi is a spirochaete that can penetrate the blood-brain barrier in early infection and can cause endothelial damage other than central nervous system lesions. We describe a clinical case of neuroborreliosis that occurred in the absence of classical erythema migrans or arthralgia. Magnetic resonance imaging findings compatible with simil-vasculitis and demyelinating lesions associated with the presence of anti-B. burgdorferi antibodies in the plasma or cerebrospinal liquid is an indication for antimicrobial treatment against B. burgdorferi. An early diagnosis and a prompt establishment of an adequate antibiotic treatment is needed for a successful recovery.
Related Concept Videos
Bacterial Phylum Spirochaetes
Rocky Mountain Spotted Fever
Bacterial Phylum Chlamydiae
Methods of Classification and Identification
Arboviral Encephalitis
Diversity of Protists I

