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Cutaneous lymphadenoma.

D J Santa Cruz1, R J Barr, J T Headington

  • 1Department of Cutaneous Pathology, St. John's Mercy Medical Center, St. Louis, Missouri 63141.

The American Journal of Surgical Pathology
|February 1, 1991
PubMed
Summary
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This study describes a rare skin tumor with basaloid features, presenting as nodules on the head and legs. Surgical excision resulted in no recurrence, suggesting a potentially benign adnexal neoplasm.

Area of Science:

  • Dermatopathology
  • Surgical Oncology
  • Neoplastic Skin Lesions

Background:

  • Cutaneous tumors present a diverse range of clinical and histopathological features.
  • Understanding rare neoplasms is crucial for accurate diagnosis and treatment.
  • Adnexal neoplasms exhibit differentiation towards skin appendages.

Purpose of the Study:

  • To present and characterize a unique type of cutaneous tumor.
  • To investigate the histopathological and immunohistochemical profile of these lesions.
  • To determine the clinical behavior and treatment outcomes of this rare tumor.

Main Methods:

  • Case series analysis of thirteen patients with unique cutaneous tumors.
  • Detailed histopathological examination of excised tumor specimens.

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  • Immunohistochemical staining for various cellular markers (keratin, common leukocytic antigen, vimentin, epithelial membrane antigen, S-100 protein).

    • Main Results:

    • Thirteen cases of solitary, skin-colored nodules, primarily on the head, were identified.
    • Histopathology revealed lobules of basaloid cells in a fibrous stroma with lymphocytic infiltrate.
    • Immunohistochemistry indicated features of adnexal neoplasm with possible immature pilosebaceous differentiation.
    • All tumors were surgically excised with no reported recurrences.

    Conclusions:

    • This unique tumor represents a distinct adnexal neoplasm with basaloid characteristics.
    • The findings suggest potential immature pilosebaceous differentiation.
    • Complete excision appears to be an effective treatment, with no observed recurrence.