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[Perioperative thromboprophylaxis in adults]
1Klinische Abteilung für Hämatologie und Hämostaseologie, Universitätsklinik für Innere Medizin I, Medizinische Universität Wien, Wien, Austria. sabine.eichinger@meduniwien.ac.at
Perioperative thrombosis prophylaxis is crucial for reducing venous thromboembolic events, especially after major surgery. This review details patient- and intervention-specific strategies for effective prevention.
Area of Science:
- Thrombosis and Hemostasis
- Vascular Surgery
- Perioperative Medicine
Context:
- Virchow's triad (altered blood flow, vascular injury, hypercoagulability) explains venous thrombosis risk.
- Perioperative venous thromboembolic events (VTE) risk ranges from <10% to >50%, highest in orthopedic and cancer surgery.
- Reducing perioperative morbidity and mortality is the primary goal of thrombosis prophylaxis.
Purpose:
- To review current strategies for perioperative thrombosis prophylaxis.
- To present recent recommendations for non-pharmacological and pharmacological prophylaxis.
- To highlight management strategies for specific surgical populations (abdominal, orthopedic, neurosurgical, cancer).
Summary:
- Discusses patient- and intervention-dependent thromboprophylactic measures.
- Covers the initiation and duration of anticoagulation therapy.
- Addresses special considerations for neurosurgical and cancer surgery patients.
Impact:
- Aims to optimize patient outcomes by minimizing VTE risk.
- Provides evidence-based guidance for clinicians managing surgical patients.
- Contributes to reducing surgical complications and improving patient safety.
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