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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Cardiovascular System Abnormal Findings I: Inspection and Palpation01:29

Cardiovascular System Abnormal Findings I: Inspection and Palpation

In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
Blood Studies I: ABG and VBG01:26

Blood Studies I: ABG and VBG

Blood studies are critical in the medical field, enabling healthcare professionals to assess a patient's health status accurately. This page will focus on two significant blood studies: Arterial Blood Gas (ABG) and Venous Blood Gas (VBG).
Arterial Blood Gas (ABG)
Arterial Blood Gas (ABG) studies are crucial for assessing the lungs' ability to supply oxygen and remove carbon dioxide, reflecting the patient's ventilation status. They also help understand the kidneys' capacity to reabsorb or...
Blood Typing01:10

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...
Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...

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Related Experiment Video

Updated: Jun 18, 2026

Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques
11:28

Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques

Published on: March 13, 2015

[Blood examination].

Masahiko Kato1

  • 1Department of Allergy and Immunology, Gunma Children's Medical Center.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|November 11, 2009
PubMed
Summary

Allergic blood tests like the radioallergosorbent test (RAST) and histamine release test (HRT) detect specific IgE antibodies and histamine release for diagnosing allergies. These sensitive methods aid in identifying allergens for conditions such as asthma and dermatitis.

Area of Science:

  • Clinical immunology
  • Allergen diagnostics
  • In vitro diagnostics

Context:

  • Allergic diseases like asthma, rhinitis, dermatitis, and food allergies require accurate allergen identification.
  • Blood examinations are crucial for diagnosing and managing allergic conditions.
  • The radioallergosorbent test (RAST) and histamine release test (HRT) are key diagnostic tools.

Purpose:

  • To review and discuss blood examination methods for allergy detection, specifically RAST and HRT.
  • To highlight the evolution and availability of different RAST systems.
  • To compare the sensitivity and limitations of RAST and HRT.

Summary:

  • Radioallergosorbent test (RAST) measures allergen-specific IgE antibodies, with advancements like CAP-RAST and MAST available.

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Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

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Last Updated: Jun 18, 2026

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A Rapid and Chemical-free Hemoglobin Assay with Photothermal Angular Light Scattering

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  • Histamine release test (HRT) measures histamine release from basophils in vitro, generally considered more sensitive than RAST.
  • HRT has limitations, including testing only ten allergens and a 10-20% non-responder rate.

    • Impact:

    • Provides a comprehensive overview of established blood tests for allergy diagnosis.
    • Informs clinicians about the capabilities and constraints of RAST and HRT.
    • Supports informed selection of diagnostic methods for allergic diseases.