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Published on: May 10, 2024
[Retinopathy in severe acute pancreatitis]
Daniela Cernea1, Aurelia Răsceanu, Florica Bârjoveanu
1Clinica Anestezie şi Terapie Intensivă, UMF Craiova. DANIELA.CERNEA@GMAIL.COM
Oftalmologia (Bucharest, Romania : 1990)
|November 11, 2009
Summary
Retina examinations in severe acute pancreatitis reveal hemorrhages and exudates, similar to Purtscher retinopathy. These findings predict severe outcomes and multiple organ failure, particularly in young males.
Area of Science:
- Ophthalmology
- Critical Care Medicine
Context:
- Severe acute pancreatitis (SAP) is a critical condition with high mortality.
- Retinal changes, including Purtscher-like retinopathy, have been observed in SAP patients.
Purpose:
- To investigate the correlation between retinal findings during ophthalmoscopy and the severity and outcome of severe acute pancreatitis.
Summary:
- Retina examination in SAP patients revealed intra/peri-retinal hemorrhages and cotton wool exudates, indicative of micro-infarction, resembling Purtscher retinopathy.
- These retinal signs were associated with severe outcomes, multiple organ failure, and mortality, especially in young males (36-56 years).
- Acute hemorrhagic retinopathy within 24 hours in septic shock patients predicted rapid mortality; severe sepsis cases showed perivascular exudates and vascular occlusion, leading to optic atrophy, unlike mild sepsis.
Impact:
- Early ophthalmoscopy in SAP can serve as a crucial predictor of disease progression and patient outcomes.
- Identifying specific retinal manifestations aids in risk stratification and management of severe acute pancreatitis.
- This study highlights the systemic impact of SAP on the retina, offering insights into its pathophysiology and prognostic indicators.
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