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Updated: Jun 18, 2026

11:15
Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
Published on: September 20, 2016
Getting knit-PI3Ky: PIK3CA mutation status to direct multimodality therapy?
Andrea P Myers1, Jeffrey A Meyerhardt, Lewis C Cantley
1Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.
Abstract:
There is high morbidity associated with local recurrence of rectal cancer. However, the adjuvant therapies given to prevent such recurrences also have significant side effects and associated risks. The ability to select patients with the highest risk of recurrence and greatest therapeutic response will improve rectal cancer care.