Newborn screening in Bangladesh

Mizanul Hasan1, Nurun Nahar, Fauzia Moslem

  • 1Institute of Nuclear Medicine & Ultrasound, Bangabandhu Sheikh Mujib Medical University, Block-D, 7th Floor, Room No. 804, Shahabagh Dhaka-1000, Bangladesh. drhasan_m@yahoo.com

Insights

Newborn screening for congenital hypothyroidism (CH) began in Bangladesh in 1999. Pilot projects screened 30,000 newborns, identifying 16 cases, paving the way for a national program.

Area of Science:

  • Public Health
  • Pediatrics
  • Endocrinology

Background:

  • Newborn screening for congenital hypothyroidism (CH) in Bangladesh commenced in 1999, supported by the International Atomic Energy Agency (IAEA).
  • Initial efforts involved two pilot projects screening approximately 30,000 newborns, identifying 16 cases of CH.
  • The program faces challenges due to Bangladesh's large population, high birth rate, low per capita income, and a high percentage of home births.

Purpose of the Study:

  • To establish and expand newborn screening for congenital hypothyroidism (CH) nationwide in Bangladesh.
  • To increase laboratory facilities and screening capacity for early detection of CH.
  • To address the public health challenge of identifying CH in a resource-limited setting.

Main Methods:

  • Implementation of pilot projects to screen newborns for CH.
  • Government approval and initiation of a national project for expanded screening in selected areas.
  • Provision of equipment, reagents, training, and expert services, initially by IAEA.

Main Results:

  • Successful completion of two pilot projects, screening around 30,000 newborns.
  • Identification of 16 newborns with congenital hypothyroidism during the pilot phases.
  • Governmental commitment to a national project targeting 200,000 newborns and enhancing laboratory infrastructure.

Conclusions:

  • Newborn screening for CH in Bangladesh has demonstrated feasibility through pilot projects.
  • A national program is underway to scale up screening efforts and improve diagnostic capabilities.
  • Overcoming socio-economic and logistical challenges is crucial for the success of nationwide newborn screening.

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