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Translating 5-HT receptor pharmacology

G J Sanger1

  • 1Wingate Institute of Neurogastroenterology, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. g.sanger@qmul.ac.uk

Neurogastroenterology and Motility
|November 13, 2009
PubMed
Summary

Researchers are developing new gastrointestinal prokinetic drugs targeting the 5-HT(4) receptor. Prucalopride shows promise for treating constipation with improved selectivity and efficacy compared to earlier compounds.

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