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Viral pathogens associated with acute respiratory infections in central vietnamese children

Lay Myint Yoshida1, Motoi Suzuki, Takeshi Yamamoto

  • 1Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.

The Pediatric Infectious Disease Journal
|November 13, 2009
PubMed

Insights

A study of hospitalized children in Vietnam found that respiratory viruses, including rhinovirus and respiratory syncytial virus, are common causes of acute respiratory infection, highlighting the need for better surveillance.

Area of Science:

  • Pediatric Infectious Diseases
  • Virology
  • Public Health

Background:

  • Acute respiratory infections (ARIs) are a major cause of childhood morbidity and mortality globally.
  • Viral pathogens are significant contributors to ARIs, particularly in developing countries.
  • Limited data exists on the specific viral etiology of ARIs in hospitalized children in Vietnam.

Purpose of the Study:

  • To investigate the prevalence of 13 common viral pathogens in hospitalized children with acute respiratory infection in Vietnam.
  • To identify the most frequent viral causes of ARI in this pediatric population.
  • To inform public health strategies for ARI prevention and control in tropical developing nations.

Main Methods:

  • Multiplex-polymerase chain reaction (PCR) was employed to detect 13 viral pathogens.
  • A cohort of 958 hospitalized children in Vietnam diagnosed with ARI was enrolled.
  • Clinical data and respiratory samples were collected for viral analysis.

Main Results:

  • A significant proportion of children (69%) had a documented viral infection.
  • Rhinovirus was the most prevalent (28%), followed by respiratory syncytial virus (23%) and influenza virus (15%).
  • Other detected viruses included adenovirus, human metapneumovirus, parainfluenza virus, and bocavirus.

Conclusions:

  • A wide spectrum of respiratory viruses circulates among hospitalized children with ARI in Vietnam.
  • These findings emphasize the critical need for enhanced surveillance systems for acute respiratory infections in tropical, developing countries.
  • Improved understanding of viral epidemiology is essential for targeted interventions and improved child health outcomes.

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