Development of amnesia in different mouse strains

D R Sinovyev1, N I Dubrovina, A V Kulikov

  • 1Research Institute of Physiology, Siberian Branch of the Russian Academy of Medical Sciences; Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk, Russia. dubrov@physiol.ru

We studied passive avoidance retrieval after amnestic stimulation (arrest in unsafe section of the experimental setup) in C57Bl/6J, BALB/c, CBA/Lac, AKR/J, DBA/2J, C3H/HeJ, and ASC/Icg mice. We demonstrated resistance to amnestic stimulation in mice with high predisposition to freezing reaction (ASC/Icg) and memory deficit in other mouse strains.

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