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Alcohol consumption and functional outcome after stroke in men
Pamela M Rist1, Klaus Berger, Julie E Buring
1Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Stroke
|November 14, 2009
Summary
Low alcohol consumption may offer modest benefits for stroke functional outcomes. This study found no strong associations between higher alcohol intake and post-stroke functional status in men.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- Alcohol consumption is linked to stroke risk, but its impact on post-stroke functional outcomes is less understood.
- Existing data on alcohol and stroke functional recovery are limited.
Purpose of the Study:
- To investigate the association between alcohol consumption levels and functional outcomes following stroke.
- To analyze the relationship between varying alcohol intake and stroke severity/disability.
Main Methods:
- Prospective cohort study of 21,860 men from the Physicians' Health Study.
- Categorized alcohol consumption (<1 drink/wk to >/=1 drink/d) and assessed functional outcomes (TIA, modified Rankin Scale).
- Employed multinomial logistic regression to analyze associations.
Main Results:
- Men consuming 1 drink/wk showed the lowest odds for any stroke outcome.
- Low alcohol intake (1 drink/wk) was associated with reduced odds for severe functional disability (mRS 4-6) after stroke.
- Higher alcohol consumption did not demonstrate a clear association with functional outcomes post-stroke.
Conclusions:
- No strong links were found between alcohol consumption and overall functional outcome after stroke.
- Modest beneficial associations may exist with very low alcohol consumption (around 1 drink/wk).
- Further research is needed to clarify the nuanced relationship between alcohol and stroke recovery.
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