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Updated: Aug 19, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
The characteristics of children with epiglottitis who develop the complication of pulmonary edema
1Medical College of Wisconsin, Department of Pediatrics, Children's Hospital of Wisconsin, Milwaukee.
Insights
Pulmonary edema is a rare complication of pediatric epiglottitis, occurring in 2.1% of cases after endotracheal intubation. This complication was observed in children with severe airway obstruction, highlighting the need for careful airway management.
Area of Science:
- Pediatric Emergency Medicine
- Critical Care
- Otolaryngology
Background:
- Epiglottitis is a serious upper airway infection in children.
- Pulmonary edema is a potential, though uncommon, complication of severe epiglottitis.
- Management protocols for pediatric epiglottitis involve airway assessment and intervention.
Observation:
- A 20-year review of 234 epiglottitis cases identified 5 children (2.1%) who developed pulmonary edema.
- Pulmonary edema occurred in children with severe airway obstruction and respiratory arrest, shortly after endotracheal intubation.
- No cases of pulmonary edema were observed in children with milder obstruction managed without an artificial airway.
Findings:
- Severe upper airway obstruction in pediatric epiglottitis is associated with the development of pulmonary edema post-endotracheal intubation.
- Two of the five affected children died from cardiorespiratory arrest secondary to airway obstruction.
- Pulmonary edema appears to be linked to significant respiratory insufficiency and the stress of airway manipulation.
Implications:
- Pulmonary edema is an uncommon but serious complication of pediatric epiglottitis, particularly after endotracheal intubation.
- Anticipating and monitoring for pulmonary edema is crucial in intubated pediatric epiglottitis patients with severe obstruction.
- While artificial airways are indicated, careful management and vigilance for this complication are essential in pediatric epiglottitis cases.
Abstract:
A review was performed of 234 consecutive cases of epiglottis that occurred during a 20-year period to delineate the rate of, and clinical characteristics associated with, the complication of pulmonary edema. As a result of the prior utilization of a "dual" management protocol, there were 170 children who received endotracheal intubation, and 64 children managed without placement of an artificial airway. In all, five children (2.1%) of varying ages developed this complication--all experienced severe airway obstruction progressing to respiratory arrest, with evidence of pulmonary edema developing shortly after endotracheal intubation. Two of these five children died due to complications resulting from upper airway obstruction-induced cardiorespiratory arrest. By contrast, no child with milder degrees of airway obstruction managed without an artificial airway exhibited clinical evidence of pulmonary edema. Several possible mechanisms for the development of this complication are described. Pulmonary edema associated with epiglottitis is an uncommon complication that can occur following endotracheal intubation in those patients with marked respiratory insufficiency. An artificial airway should be instituted in all cases of pediatric epiglottitis--the potential complication of pulmonary edema should be anticipated before placement of an artificial airway, especially in those patients with a severe degree of upper airway obstruction.
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