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Azido derivative of tricarboxylic acid for photoaffinity labeling
A Szewczyk1, D Claeys, W Mertens
1Institut für Biochemie und Molekularbiologie, Universität Bern, Switzerland.
Biochimica Et Biophysica Acta
|January 23, 1991
Abstract:
A new photoaffinity probe, 5-(1-hydroxy-4-azidophenylazo)-1,2,3-benzenetricarboxylic acid, was synthesized and characterized. This reagent can be potentially used in photoaffinity labeling of the mitochondrial tricarboxylate carrier, as well as of enzymes interacting with tricarboxylic acids. Inhibition and labeling of the mitochondrial tricarboxylate carrier is presented.