[Lemierre syndrome]

Area of Science:

• Infectious Diseases
• Otolaryngology
• Vascular Surgery

Context:

• Lemierre syndrome is a rare but severe condition characterized by cervicofacial infection, internal jugular vein thrombosis, and metastatic infections.
• Fusobacterium necrophorum is the primary pathogen implicated in Lemierre syndrome.
• Historically associated with high mortality before antibiotics, the incidence of Lemierre syndrome has increased recently.

Purpose:

• To review the literature on Lemierre syndrome.
• To update knowledge on the epidemiologic, clinical, and therapeutic aspects of this reemerging disease.

Summary:

• Lemierre syndrome involves primary cervicofacial infection leading to internal jugular vein thrombosis and potential metastatic spread, commonly to the lungs.
• While recovery is typical, it often requires prolonged convalescence and surgical intervention.
• The increasing incidence of Lemierre syndrome necessitates a comprehensive understanding of its current presentation and management.

Impact:

• Provides an updated resource for clinicians managing Lemierre syndrome.
• Highlights the reemergence of a previously rare but dangerous infection.
• Emphasizes the need for timely diagnosis and appropriate therapeutic strategies, including potential surgical interventions.